Bernd K. Gilsbach

Otfried Müller Str. 23
Tuebingen, BW 72076, Germany

Last Updated: 09/26/2026

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Found 14 publications

Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism.

Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism.

Journal: eLife

Published: December 19, 2024

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.

Journal: Brain : a journal of neurology

Published: August 27, 2024

C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis.

C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis.

Journal: Frontiers in immunology

Published: October 20, 2022

Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.

Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.

Journal: ACS chemical biology

Published: September 09, 2021

Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria.

Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria.

Journal: Current biology : CB

Published: October 25, 2019

Biochemical and kinetic properties of the complex Roco G-protein cycle.

Biochemical and kinetic properties of the complex Roco G-protein cycle.

Journal: Biological chemistry

Published: April 18, 2018

Regulation of LRRK2: insights from structural and biochemical analysis.

Regulation of LRRK2: insights from structural and biochemical analysis.

Journal: Biological chemistry

Published: January 21, 2018

First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein.

First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein.

Journal: Biochemical Society transactions

Published: August 04, 2016

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 01, 2016

Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations.

Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations.

Journal: Bioscience reports

Published: May 20, 2015

Structural Characterization of LRRK2 Inhibitors.

Structural Characterization of LRRK2 Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 22, 2015

Revisiting the Roco G-protein cycle.

Revisiting the Roco G-protein cycle.

Journal: The Biochemical journal

Published: October 16, 2014

Showing 1-12 of 14

Last Updated: 09/26/2026