Bernhard Reis

Basel, BS 4070, Switzerland

Last Updated: 09/26/2026

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Found 17 publications

In vitro and in vivo derived macrophages occupy distinct phenotypic states.

In vitro and in vivo derived macrophages occupy distinct phenotypic states.

Journal: bioRxiv : the preprint server for biology

Published: September 26, 2025

Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial.

Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial.

Journal: Nature cancer

Published: December 19, 2024

A randomized, double-blind, placebo-controlled, multiple dose, parallel study to investigate the effects of a cathepsin S inhibitor in celiac disease.

A randomized, double-blind, placebo-controlled, multiple dose, parallel study to investigate the effects of a cathepsin S inhibitor in celiac disease.

Journal: Clinical and translational science

Published: February 12, 2024

Tumor beta2-microglobulin and HLA-A expression is increased by immunotherapy and can predict response to CIT in association with other biomarkers.

Tumor beta2-microglobulin and HLA-A expression is increased by immunotherapy and can predict response to CIT in association with other biomarkers.

Journal: Frontiers in immunology

Published: August 29, 2023

Facts and Hopes on Biomarkers for Successful Early Clinical Immunotherapy Trials: Innovative Patient Enrichment Strategies.

Facts and Hopes on Biomarkers for Successful Early Clinical Immunotherapy Trials: Innovative Patient Enrichment Strategies.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: May 20, 2023

Biomarker Technologies to Support Early Clinical Immuno-oncology Development: Advances and Interpretation.

Biomarker Technologies to Support Early Clinical Immuno-oncology Development: Advances and Interpretation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: November 24, 2020

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages.

Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology

Published: May 23, 2019

Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome.

Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome.

Journal: Arthritis research & therapy

Published: February 21, 2019

Case-control Indian buffet process identifies biomarkers of response to Codrituzumab.

Case-control Indian buffet process identifies biomarkers of response to Codrituzumab.

Journal: BMC cancer

Published: November 20, 2018

Tissue-Specific Immunoregulation: A Call for Better Understanding of the "Immunostat" in the Context of Cancer.

Tissue-Specific Immunoregulation: A Call for Better Understanding of the "Immunostat" in the Context of Cancer.

Journal: Cancer discovery

Published: November 22, 2017

Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages.

Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages.

Journal: Biochemical pharmacology

Published: July 05, 2017

Pharmacodynamic Monitoring of RO5459072, a Small Molecule Inhibitor of Cathepsin S.

Pharmacodynamic Monitoring of RO5459072, a Small Molecule Inhibitor of Cathepsin S.

Journal: Frontiers in immunology

Published: April 02, 2017

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Last Updated: 09/26/2026