Biagina Marrocco

Via Ferrata 9
Pavia, 27100, Italy

Last Updated: 09/26/2026

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Found 17 publications

Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.

Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.

Journal: European journal of medicinal chemistry

Published: January 11, 2022

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.

Journal: Cell reports

Published: January 14, 2019

Correction to 'Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells'.

Correction to 'Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells'.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: August 01, 2018

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Journal: European journal of medicinal chemistry

Published: July 24, 2018

Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.

Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: September 11, 2017

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells.

Journal: Oncotarget

Published: November 18, 2016

The growing structural and functional complexity of the LSD1/KDM1A histone demethylase.

The growing structural and functional complexity of the LSD1/KDM1A histone demethylase.

Journal: Current opinion in structural biology

Published: July 06, 2016

Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.

Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.

Journal: Science advances

Published: May 06, 2016

Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model.

Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model.

Journal: Autoimmunity

Published: January 21, 2016

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.

Journal: Journal of medicinal chemistry

Published: December 26, 2015

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

Journal: Journal of medicinal chemistry

Published: December 19, 2015

Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents.

Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents.

Journal: ACS chemical biology

Published: September 01, 2015

Showing 1-12 of 17

Last Updated: 09/26/2026