Bing Zhang
103 Wenhua Road
Shenyang, 110016, China
Shenyang, 110016, China
Last Updated: 09/26/2026
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Found 26 publications
Discovery of 1-(4-cyanopyrimidin-2-yl)-1H-pyrazole-4-carboxylic acids as potent xanthine oxidase inhibitors via molecular cleavage and reassembly of allopurinol as a key strategy.
Journal: Bioorganic chemistry
Published: October 21, 2025
Design, Synthesis, and Biological Evaluation of Heterocycle-Fused Celastrol Derivatives as Potent Antiosteoporosis Agents by Blocking RANKL-Induced Activation of the NF-κB and MAPK Signaling Pathways.
Journal: Journal of medicinal chemistry
Published: August 11, 2025
Discovery of 1-Difluoromethyl-3-(3-cyanophenyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazin-8-(7H)-one as a Potent P2Y1 Antagonist for the Treatment of Ischemic Stroke and Myocardial Infarction.
Journal: Journal of medicinal chemistry
Published: August 06, 2025
Design, Synthesis, and Biological Evaluation of 4-(Difluoromethyl)-1H-imidazole-5-carboxylic Acids/4-(3-Cyanophenoxy)pyrimidine-5-carboxylic Acids as P2Y1 Receptor Antagonists for Ischemic Stroke Treatment.
Journal: Journal of medicinal chemistry
Published: May 15, 2025
Design, synthesis and biological evaluation of 2-[1-(pyridin-2-ylmethyl)-1H-pyrazole-3-carboxamido]benzoic acids as promising urate transporter 1 inhibitors with potential nephroprotective efficacy for the treatment of hyperuricemic nephropathy.
Journal: European journal of medicinal chemistry
Published: January 05, 2025
A patent review of xanthine oxidase inhibitors (2021-present).
Journal: Expert opinion on therapeutic patents
Published: December 28, 2024
Scaffold Hopping of Pristimerin Provides Derivatives Containing a Privileged Quinoxaline Substructure as Potent Autophagy Inducers in Breast Cancer Cells.
Journal: Journal of natural products
Published: August 06, 2024
Identification of 5-[5-cyano-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamido] thiazole-4-carboxylic acid as a promising dual inhibitor of urate transporter 1 and xanthine oxidase.
Journal: European journal of medicinal chemistry
Published: March 23, 2023
Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5-ASA-PABA-MAC and 5-ASA-PABA-Diamine for the Treatment of Ulcerative Colitis.
Journal: Journal of medicinal chemistry
Published: March 11, 2022
Thiazolidinedione-Based Structure Modification of Celastrol Provides Thiazolidinedione-Conjugated Derivatives as Potent Agents against Non-Small-Cell Lung Cancer Cells through a Mitochondria-Mediated Apoptotic Pathway.
Journal: Journal of natural products
Published: March 08, 2022
Overload performance study and fabrication of the capacitive pressure-sensitive chip with linkage film.
Journal: The Review of scientific instruments
Published: February 02, 2022
Last Updated: 09/26/2026