Birgitta R. Knudsen

Arhus, 8000, Denmark

Last Updated: 09/26/2026

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Found 59 publications

Synthesis and biological evaluation of novel fused pyridopyrimidine derivatives as topoisomerase I inhibitors and as potential antitumor agents: promising results in lung, ovary and gastric cancer.

Synthesis and biological evaluation of novel fused pyridopyrimidine derivatives as topoisomerase I inhibitors and as potential antitumor agents: promising results in lung, ovary and gastric cancer.

Journal: European journal of medicinal chemistry

Published: December 29, 2025

Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents.

Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents.

Journal: ChemMedChem

Published: September 03, 2025

A cellular system to study responses to a collision between the transcription complex and a protein-bound nick in the DNA template.

A cellular system to study responses to a collision between the transcription complex and a protein-bound nick in the DNA template.

Journal: FEBS letters

Published: January 13, 2025

Phosphine Oxide Indenoquinoline Derivatives: Synthesis and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative Agents.

Phosphine Oxide Indenoquinoline Derivatives: Synthesis and Biological Evaluation as Topoisomerase I Inhibitors and Antiproliferative Agents.

Journal: Molecules (Basel, Switzerland)

Published: November 22, 2024

Non-Invasive Malaria Detection in Sub-Saharan Africa Using a DNA-Based Sensor System.

Non-Invasive Malaria Detection in Sub-Saharan Africa Using a DNA-Based Sensor System.

Journal: Sensors (Basel, Switzerland)

Published: November 04, 2024

Hydrogel bead-based isothermal detection (BEAD-ID) for assessing the activity of DNA-modifying enzymes.

Hydrogel bead-based isothermal detection (BEAD-ID) for assessing the activity of DNA-modifying enzymes.

Journal: iScience

Published: June 20, 2024

Topoisomerase 1 Activity Is Reduced in Response to Thermal Stress in Fruit Flies and in Human HeLa Cells.

Topoisomerase 1 Activity Is Reduced in Response to Thermal Stress in Fruit Flies and in Human HeLa Cells.

Journal: Biosensors

Published: September 22, 2023

Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.

Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: February 21, 2023

Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples.

Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples.

Journal: Journal of visualized experiments : JoVE

Published: December 19, 2022

MUS81 cleaves TOP1-derived lesions and other DNA-protein cross-links.

MUS81 cleaves TOP1-derived lesions and other DNA-protein cross-links.

Journal: BMC biology

Published: September 16, 2022

Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts.

Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts.

Journal: Sensors (Basel, Switzerland)

Published: August 26, 2022

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX.

Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX.

Journal: Cells

Published: March 30, 2022

Showing 1-12 of 59

Last Updated: 09/26/2026