Birk Poller

Basel, BS 4056, Switzerland

Last Updated: 09/26/2026

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Found 32 publications

Quantifying Transporter Activity: An Absolute Scaling Approach Using Digoxin.

Quantifying Transporter Activity: An Absolute Scaling Approach Using Digoxin.

Journal: Molecular pharmaceutics

Published: June 15, 2026

Microfluidic liver-chip to predict clinical drug-drug interaction net effects for precipitant drugs with dual CYP3A4 inhibition and induction potential.

Microfluidic liver-chip to predict clinical drug-drug interaction net effects for precipitant drugs with dual CYP3A4 inhibition and induction potential.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: May 08, 2026

Navigating ADME profiling challenges in microphysiological systems: Evaluation of a liver-chip model for clearance prediction.

Navigating ADME profiling challenges in microphysiological systems: Evaluation of a liver-chip model for clearance prediction.

Journal: Journal of pharmaceutical sciences

Published: November 14, 2025

Intestinal Cells-on-Chip for Permeability Studies.

Intestinal Cells-on-Chip for Permeability Studies.

Journal: Micromachines

Published: October 31, 2024

Improving In Vitro-In Vivo Extrapolation of Clearance Using Rat Liver Microsomes for Highly Plasma Protein-Bound Molecules.

Improving In Vitro-In Vivo Extrapolation of Clearance Using Rat Liver Microsomes for Highly Plasma Protein-Bound Molecules.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: November 03, 2023

Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Journal: Archives of toxicology

Published: September 28, 2023

Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC).

Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC).

Journal: Archives of toxicology

Published: September 28, 2023

LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.

LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.

Journal: Clinical and translational science

Published: July 20, 2023

The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development.

The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development.

Journal: Pharmacological research

Published: April 19, 2023

Absorption, Distribution, Metabolism, and Excretion of [14C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies.

Absorption, Distribution, Metabolism, and Excretion of [14C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: February 06, 2023

Validation of personal protective equipment ensembles, incorporating powered air-purifying respirators protected from contamination, for the care of patients with high-consequence infectious diseases.

Validation of personal protective equipment ensembles, incorporating powered air-purifying respirators protected from contamination, for the care of patients with high-consequence infectious diseases.

Journal: The Journal of hospital infection

Published: October 24, 2022

Simplifying the Extended Clearance Concept Classification System (EC3S) to Guide Clearance Prediction in Drug Discovery.

Simplifying the Extended Clearance Concept Classification System (EC3S) to Guide Clearance Prediction in Drug Discovery.

Journal: Pharmaceutical research

Published: October 18, 2022

Showing 1-12 of 32

Last Updated: 09/26/2026