Bob Van De Water
Leiden, ZH 2333CC, Netherlands
Last Updated: 09/26/2026
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Found 28 publications
A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation.
Journal: Archives of toxicology
Published: July 15, 2025
Disrupting CDK9 activity suppresses triple-negative breast cancer and is enhanced by EGFR Inhibition.
Journal: Cellular oncology (Dordrecht, Netherlands)
Published: May 02, 2025
Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage, and regeneration response after cisplatin.
Journal: Cell biology and toxicology
Published: September 20, 2024
Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.
Journal: Breast cancer research : BCR
Published: January 16, 2023
A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer.
Journal: Biochemical pharmacology
Published: June 10, 2022
Evaluation of an imaging-based in vitro screening platform for estrogenic activity with OECD reference chemicals.
Journal: Toxicology in vitro : an international journal published in association with BIBRA
Published: November 06, 2021
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
Journal: Archives of toxicology
Published: August 13, 2021
Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury.
Journal: Biochemical pharmacology
Published: February 17, 2021
Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.
Journal: Journal of experimental & clinical cancer research : CR
Published: October 29, 2020
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.
Journal: Oncogene
Published: September 26, 2019
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project.
Journal: Archives of toxicology
Published: September 18, 2019
Last Updated: 09/26/2026