Bogumil Kaczkowski

AstraZeneca R&D
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 24 publications

Targeting dysregulated epigenetic and transcription factor networks in KMT2A-rearranged AML using iPSC models.

Targeting dysregulated epigenetic and transcription factor networks in KMT2A-rearranged AML using iPSC models.

Journal: Blood neoplasia
Published: May 23, 2025

Correction: A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Correction: A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Journal: PloS one
Published: March 20, 2025

A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

A statistical simulation model to guide the choices of analytical methods in arrayed CRISPR screen experiments.

Journal: PloS one
Published: May 06, 2024

Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach.

Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biology approach.

Journal: Molecular metabolism
Published: September 19, 2023

Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.

Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.

Journal: BMC genomics
Published: July 26, 2023

xcore: an R package for inference of gene expression regulators.

xcore: an R package for inference of gene expression regulators.

Journal: BMC bioinformatics
Published: July 03, 2022

Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML.

Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML.

Journal: Translational oncology
Published: November 19, 2021

Inducing human retinal pigment epithelium-like cells from somatic tissue.

Inducing human retinal pigment epithelium-like cells from somatic tissue.

Journal: Stem cell reports
Published: April 01, 2021

Development of p53 knockout U87MG cell line for unbiased drug delivery testing system using CRISPR-Cas9 and transcriptomic analysis.

Development of p53 knockout U87MG cell line for unbiased drug delivery testing system using CRISPR-Cas9 and transcriptomic analysis.

Journal: Journal of biotechnology
Published: October 06, 2020

Functional annotation of human long noncoding RNAs via molecular phenotyping.

Functional annotation of human long noncoding RNAs via molecular phenotyping.

Journal: Genome research
Published: July 12, 2019

JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.

JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.

Journal: Epigenetics
Published: August 07, 2018

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages.

Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages.

Journal: Scientific reports
Published: August 08, 2017
Showing 1-12 of 24

Last Updated: 09/26/2026