Bohumil Fafilek

Brno, JM 62500, Czech Republic

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 25 publications

Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential.

Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential.

Journal: Bone reports

Published: November 02, 2025

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors.

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors.

Journal: Cell communication and signaling : CCS

Published: November 28, 2024

Increased thermal stability of FGF10 leads to ectopic signaling during development.

Increased thermal stability of FGF10 leads to ectopic signaling during development.

Journal: Cellular and molecular life sciences : CMLS

Published: August 21, 2024

Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.

Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Published: August 16, 2024

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2.

Journal: Journal of medicinal chemistry

Published: July 18, 2024

Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.

Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.

Journal: Communications biology

Published: June 27, 2024

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.

Journal: Molecular therapy. Nucleic acids

Published: June 18, 2024

Ligand bias underlies differential signaling of multiple FGFs via FGFR1.

Ligand bias underlies differential signaling of multiple FGFs via FGFR1.

Journal: eLife

Published: April 03, 2024

FGFR2 residence in primary cilia is necessary for epithelial cell signaling.

FGFR2 residence in primary cilia is necessary for epithelial cell signaling.

Journal: The Journal of cell biology

Published: November 07, 2023

LuminoCell: a versatile and affordable platform for real-time monitoring of luciferase-based reporters.

LuminoCell: a versatile and affordable platform for real-time monitoring of luciferase-based reporters.

Journal: Life science alliance

Published: February 23, 2022

Expanding horizons of achondroplasia treatment: current options and future developments.

Expanding horizons of achondroplasia treatment: current options and future developments.

Journal: Osteoarthritis and cartilage

Published: August 03, 2021

4-PBA Treatment Improves Bone Phenotypes in the Aga2 Mouse Model of Osteogenesis Imperfecta.

4-PBA Treatment Improves Bone Phenotypes in the Aga2 Mouse Model of Osteogenesis Imperfecta.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Published: December 30, 2020

Showing 1-12 of 25

Last Updated: 09/26/2026