Brad G. Hoffman

Vancouver, BC, Canada

Last Updated: 09/26/2026

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Found 17 publications

WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.

WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.

Journal: bioRxiv : the preprint server for biology

Published: November 01, 2024

Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice.

Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice.

Journal: Diabetologia

Published: July 24, 2022

H3K4 Trimethylation Is Required for Postnatal Pancreatic Endocrine Cell Functional Maturation.

H3K4 Trimethylation Is Required for Postnatal Pancreatic Endocrine Cell Functional Maturation.

Journal: Diabetes

Published: November 30, 2020

Metabolism as a central regulator of β-cell chromatin state.

Metabolism as a central regulator of β-cell chromatin state.

Journal: The FEBS journal

Published: June 19, 2020

Correction to: PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice.

Correction to: PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice.

Journal: Diabetologia

Published: March 16, 2020

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.

Journal: Diabetologia

Published: May 04, 2019

TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation.

TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation.

Journal: Cell reports

Published: May 31, 2018

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.

Journal: Cell metabolism

Published: October 13, 2017

Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction.

Myt3 suppression sensitizes islet cells to high glucose-induced cell death via Bim induction.

Journal: Cell death & disease

Published: January 08, 2016

Chromatin Regulators in Pancreas Development and Diabetes.

Chromatin Regulators in Pancreas Development and Diabetes.

Journal: Trends in endocrinology and metabolism: TEM

Published: October 26, 2015

Myt3 Mediates Laminin-V/Integrin-β1-Induced Islet-Cell Migration via Tgfbi.

Myt3 Mediates Laminin-V/Integrin-β1-Induced Islet-Cell Migration via Tgfbi.

Journal: Molecular endocrinology (Baltimore, Md.)

Published: July 16, 2015

The TrxG Complex Mediates Cytokine Induced De Novo Enhancer Formation in Islets.

The TrxG Complex Mediates Cytokine Induced De Novo Enhancer Formation in Islets.

Journal: PloS one

Published: February 27, 2015

Showing 1-12 of 17

Last Updated: 09/26/2026