Brendon J. Monahan

Melbourne, VIC 3000, Australia

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 20 publications

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.

Journal: bioRxiv : the preprint server for biology

Published: December 23, 2024

Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.

Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.

Journal: Cancer discovery

Published: October 22, 2024

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.

Journal: Cell chemical biology

Published: July 06, 2022

Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest.

Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest.

Journal: Cell death & disease

Published: April 28, 2021

Crystal structures of human ENPP1 in apo and bound forms.

Crystal structures of human ENPP1 in apo and bound forms.

Journal: Acta crystallographica. Section D, Structural biology

Published: April 26, 2020

Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.

Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.

Journal: Journal of medicinal chemistry

Published: March 03, 2020

Adaptation to Industrial Stressors Through Genomic and Transcriptional Plasticity in a Bioethanol Producing Fission Yeast Isolate.

Adaptation to Industrial Stressors Through Genomic and Transcriptional Plasticity in a Bioethanol Producing Fission Yeast Isolate.

Journal: G3 (Bethesda, Md.)

Published: February 23, 2020

Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation.

Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation.

Journal: Cell reports

Published: October 18, 2019

Fragment screening for a protein-protein interaction inhibitor to WDR5.

Fragment screening for a protein-protein interaction inhibitor to WDR5.

Journal: Structural dynamics (Melville, N.Y.)

Published: August 02, 2019

Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.

Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.

Journal: Journal of medicinal chemistry

Published: July 02, 2019

Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Journal: Cancer research

Published: June 05, 2019

A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe.

A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe.

Journal: BMC genomics

Published: January 07, 2019

Showing 1-12 of 20

Last Updated: 09/26/2026