Brian A. Macvicar

Vancouver, BC, Canada

Last Updated: 09/26/2026

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Found 61 publications

A Microglia-Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses.

A Microglia-Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses.

Journal: Glia
Published: January 20, 2026

White matter interactome in vascular dementia.

White matter interactome in vascular dementia.

Journal: Cell research
Published: September 17, 2025

Generation of 3D Human iPSC-Derived Multi-Cell Type Neurospheres for Studying Neuron, Astrocyte, and Microglia Crosstalk.

Generation of 3D Human iPSC-Derived Multi-Cell Type Neurospheres for Studying Neuron, Astrocyte, and Microglia Crosstalk.

Journal: Bio-protocol
Published: July 30, 2025

Single-Cell Approaches Define the Murine Leptomeninges: Cortical Brain Interface as a Distinct Cellular Neighborhood Composed of Neural and Non-neural Cell Types.

Single-Cell Approaches Define the Murine Leptomeninges: Cortical Brain Interface as a Distinct Cellular Neighborhood Composed of Neural and Non-neural Cell Types.

Journal: eNeuro
Published: January 28, 2025

A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis.

A 3D human iPSC-derived multi-cell type neurosphere system to model cellular responses to chronic amyloidosis.

Journal: Journal of neuroinflammation
Published: January 18, 2025

Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation.

Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation.

Journal: JCI insight
Published: June 24, 2024

Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.

Astrocyte Regulation of Cerebral Blood Flow in Health and Disease.

Journal: Cold Spring Harbor perspectives in biology
Published: February 05, 2024

Chronic pregabalin treatment protects against spreading depolarization and alters hippocampal synaptic characteristics in a model of familial hemiplegic migraine-type 1.

Chronic pregabalin treatment protects against spreading depolarization and alters hippocampal synaptic characteristics in a model of familial hemiplegic migraine-type 1.

Journal: Molecular brain
Published: April 25, 2023

Modelling Microglial Innate Immune Memory In Vitro: Understanding the Role of Aerobic Glycolysis in Innate Immune Memory.

Modelling Microglial Innate Immune Memory In Vitro: Understanding the Role of Aerobic Glycolysis in Innate Immune Memory.

Journal: International journal of molecular sciences
Published: April 20, 2023

Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts.

Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts.

Journal: Cell reports
Published: December 02, 2022

Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress.

Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress.

Journal: Redox biology
Published: June 14, 2022

The Oral and Fecal Microbiota in a Canadian Cohort of Alzheimer's Disease.

The Oral and Fecal Microbiota in a Canadian Cohort of Alzheimer's Disease.

Journal: Journal of Alzheimer's disease : JAD
Published: March 11, 2022
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Last Updated: 09/26/2026