Brian C. Grieb

Oncology
322 22nd Ave N
Ste 400
Nashville, TN 37203

Last Updated: 09/26/2026

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Found 17 publications

5-Azacytidine incorporation into mRNAs disrupts translation and induces ribosome collisions.

5-Azacytidine incorporation into mRNAs disrupts translation and induces ribosome collisions.

Journal: bioRxiv : the preprint server for biology
Published: April 10, 2026

Optimization of first-line treatment selection in advanced pancreatic adenocarcinoma using artificial intelligence.

Optimization of first-line treatment selection in advanced pancreatic adenocarcinoma using artificial intelligence.

Journal: NPJ precision oncology
Published: February 09, 2026

Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies.

Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 21, 2024

Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.

Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.

Journal: eLife
Published: April 29, 2024

Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.

Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.

Journal: bioRxiv : the preprint server for biology
Published: August 07, 2023

New Opportunities for Minimizing Toxicity in Rectal Cancer Management.

New Opportunities for Minimizing Toxicity in Rectal Cancer Management.

Journal: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Published: June 12, 2023

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 27, 2022

MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging.

MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging.

Journal: Biology
Published: April 16, 2022

Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells.

Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells.

Journal: NAR cancer
Published: June 29, 2021

HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles.

HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles.

Journal: Current treatment options in oncology
Published: May 23, 2021

Evolving Landscape of Systemic Therapy for Hepatocellular Carcinoma: Breakthroughs, Toxicities, and Future Frontiers.

Evolving Landscape of Systemic Therapy for Hepatocellular Carcinoma: Breakthroughs, Toxicities, and Future Frontiers.

Journal: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
Published: May 18, 2019

The View from My Seat.

The View from My Seat.

Journal: Journal of palliative medicine
Published: February 14, 2017
Showing 1-12 of 17

Last Updated: 09/26/2026