Brian J. Huntly

Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia.

Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia.

Journal: Leukemia
Published: October 20, 2025

Inhibition of p300/CREBBP catalytic activity drives context-dependent transcriptional activation in AML.

Inhibition of p300/CREBBP catalytic activity drives context-dependent transcriptional activation in AML.

Journal: Blood
Published: October 03, 2025

DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells.

DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells.

Journal: bioRxiv : the preprint server for biology
Published: October 16, 2024

Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.

Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.

Journal: Science advances
Published: August 03, 2022

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.

Journal: Leukemia
Published: October 12, 2021

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.

Journal: Molecular cell
Published: March 29, 2021

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy.

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy.

Journal: Cell metabolism
Published: December 10, 2019

Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.

Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.

Journal: eLife
Published: September 09, 2019

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.

A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients.

Journal: Leukemia
Published: January 13, 2017

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.

Journal: Cell reports
Published: January 19, 2016

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

Journal: BMC cancer
Published: April 26, 2015

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia.

Journal: Blood
Published: April 26, 2014
Showing 1-12 of 15

Last Updated: 09/26/2026