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Dr. Brian M. Smith
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Brian M. Smith
Family Medicine
636-625-2662
400 Medical Plaza
Suite 200
Lake St. Louis, MO 63367
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Last Updated: 09/26/2026
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Identification of biaryl sulfone derivatives as antagonists of the histamine H₃ receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916).
Identification of biaryl sulfone derivatives as antagonists of the histamine H₃ receptor: discovery of (R)-1-(2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916).
Journal:
Bioorganic & medicinal chemistry letters
Published:
October 24, 2011
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Last Updated: 09/26/2026