Brian R. Rosborough

Brian R. Rosborough

Pulmonary Medicine

3 Saint Francis Way, Suite 206
Cranberry Twp, PA 16066

Last Updated: 09/26/2026

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Found 20 publications

COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes.

COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes.

Journal: Annals of the American Thoracic Society

Published: February 05, 2021

Single cell RNA sequencing identifies an early monocyte gene signature in acute respiratory distress syndrome.

Single cell RNA sequencing identifies an early monocyte gene signature in acute respiratory distress syndrome.

Journal: JCI insight

Published: December 12, 2019

IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation.

IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation.

Journal: Journal of hepatology

Published: March 23, 2017

A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.

A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: April 20, 2016

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: October 07, 2014

IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells.

IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: September 14, 2014

A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells.

A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells.

Journal: Kidney international

Published: April 01, 2014

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: March 19, 2014

Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection.

Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Published: October 08, 2013

Regulatory myeloid cells in transplantation.

Regulatory myeloid cells in transplantation.

Journal: Transplantation

Published: October 05, 2013

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection.

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection.

Journal: Hepatology (Baltimore, Md.)

Published: August 14, 2013

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury.

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: August 02, 2013

Showing 1-12 of 20

Last Updated: 09/26/2026