Brigitte L. Theriault

661 University Avenue, Suite 510
Toronto, ON M5G0A3, Canada

Last Updated: 09/26/2026

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Found 16 publications

Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.

Discovery of pyrrolopyrimidinone inhibitors of the BCL6-SMRT corepressor interaction.

Journal: Bioorganic & medicinal chemistry

Published: December 16, 2025

Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.

Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: October 27, 2025

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

Journal: Communications biology

Published: January 17, 2025

CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells.

CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells.

Journal: Scientific reports

Published: March 08, 2024

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor.

Journal: ACS medicinal chemistry letters

Published: November 30, 2022

Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels.

Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels.

Journal: Biomaterials

Published: November 03, 2022

Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.

Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.

Journal: Journal of molecular biology

Published: July 29, 2021

A drug discovery platform to identify compounds that inhibit EGFR triple mutants.

A drug discovery platform to identify compounds that inhibit EGFR triple mutants.

Journal: Nature chemical biology

Published: October 18, 2017

Corrigendum: Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients.

Corrigendum: Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients.

Journal: Nature protocols

Published: August 28, 2015

The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells.

The role of KIF14 in patient-derived primary cultures of high-grade serous ovarian cancer cells.

Journal: Journal of ovarian research

Published: July 30, 2014

Establishment of primary cultures from ovarian tumor tissue and ascites fluid.

Establishment of primary cultures from ovarian tumor tissue and ascites fluid.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 06, 2013

Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer.

Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer.

Journal: PloS one

Published: June 21, 2013

Showing 1-12 of 16

Last Updated: 09/26/2026