Bruce E. Clurman
Oncology
University Of Washington Medical Ctr
1959 Ne Pacific St
Seattle, WA 98195
1959 Ne Pacific St
Seattle, WA 98195
Last Updated: 09/26/2026
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Found 26 publications
Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV+ tumors.
Journal: bioRxiv : the preprint server for biology
Published: March 27, 2026
Subtype-Specific Dependencies and Drug Vulnerabilities Enable Precision Therapeutics in Head and Neck Cancer.
Journal: bioRxiv : the preprint server for biology
Published: December 22, 2025
Transcriptional states define dependencies and therapeutic vulnerabilities in head and neck cancer.
Journal: NPJ precision oncology
Published: November 10, 2025
Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Journal: Science advances
Published: January 28, 2022
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.
Journal: eLife
Published: September 30, 2021
FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: October 23, 2020
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
Journal: Nature communications
Published: April 24, 2020
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation.
Journal: Science advances
Published: October 29, 2019
Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP.
Journal: PLoS pathogens
Published: July 13, 2018
Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: May 08, 2018
Last Updated: 09/26/2026