Bruno Pagano

Via D. Montesano 49
Naples, 80131, Italy

Last Updated: 09/26/2026

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Found 83 publications

Combined All-Atom Simulations and Biophysical Assays Uncover Loop-Driven Stabilization in the HRAS i-motif.

Combined All-Atom Simulations and Biophysical Assays Uncover Loop-Driven Stabilization in the HRAS i-motif.

Journal: Journal of chemical information and modeling

Published: March 04, 2026

Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers.

Ligands reshape the compactness, stability, and topology of telomeric G-quadruplex dimers.

Journal: Nucleic acids research

Published: December 05, 2025

Design and evaluation of dual-functional aptamer-peptide conjugates as a platform for targeted cancer therapy.

Design and evaluation of dual-functional aptamer-peptide conjugates as a platform for targeted cancer therapy.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: November 06, 2025

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle-Based Delivery.

Therapeutic Oligonucleotides for Neurodegenerative Diseases: Aptamer Strategies and Clay Nanoparticle-Based Delivery.

Journal: Chemical record (New York, N.Y.)

Published: June 01, 2025

From alkylating to shape-shifting G-quadruplex ligands: the RHAU peptide story.

From alkylating to shape-shifting G-quadruplex ligands: the RHAU peptide story.

Journal: Nucleic acids research

Published: April 14, 2025

Investigating temperature-induced unfolding pathways of DNA G-quadruplexes via 2D UV resonant Raman spectroscopy.

Investigating temperature-induced unfolding pathways of DNA G-quadruplexes via 2D UV resonant Raman spectroscopy.

Journal: International journal of biological macromolecules

Published: April 14, 2025

Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration.

Unveiling the biological effects of DNA G-quadruplex ligands through multi-omics data integration.

Journal: International journal of biological macromolecules

Published: February 03, 2025

Modulating TERRA G-quadruplexes with ligands: impact on telomeric DNA:RNA hybrids and ALT mechanisms.

Modulating TERRA G-quadruplexes with ligands: impact on telomeric DNA:RNA hybrids and ALT mechanisms.

Journal: Nucleic acids research

Published: January 07, 2025

Design, Synthesis, and Anticancer Activity of Drug-like Iron Chelators/G-Quadruplex Binders as Synergic Dual Targeting Agents.

Design, Synthesis, and Anticancer Activity of Drug-like Iron Chelators/G-Quadruplex Binders as Synergic Dual Targeting Agents.

Journal: Journal of medicinal chemistry

Published: January 01, 2025

Repurposing FDA-approved drugs to target G-quadruplexes in breast cancer.

Repurposing FDA-approved drugs to target G-quadruplexes in breast cancer.

Journal: European journal of medicinal chemistry

Published: December 01, 2024

Expanding the Functions of KHSRP Protein: Insights into DNA G-Quadruplex Binding.

Expanding the Functions of KHSRP Protein: Insights into DNA G-Quadruplex Binding.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: August 22, 2024

Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents.

Sensitization of melanoma cells to standard chemotherapy: G-quadruplex binders as synergistic agents.

Journal: NAR cancer

Published: July 27, 2024

Showing 1-12 of 83

Last Updated: 09/26/2026