Bryan Serrels

Edinburgh, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 30 publications

Targeting the PREX2/RAC1/PI3Kβ Signaling Axis Confers Sensitivity to Clinically Relevant Therapeutic Approaches in Melanoma.

Targeting the PREX2/RAC1/PI3Kβ Signaling Axis Confers Sensitivity to Clinically Relevant Therapeutic Approaches in Melanoma.

Journal: Cancer research
Published: September 14, 2023

Harnessing CD3 diversity to optimize CAR T cells.

Harnessing CD3 diversity to optimize CAR T cells.

Journal: Nature immunology
Published: December 14, 2022

Editor's Note: Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior.

Editor's Note: Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior.

Journal: Cancer research
Published: July 05, 2022

ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.

ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.

Journal: Development (Cambridge, England)
Published: January 20, 2022

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs.

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs.

Journal: Scientific reports
Published: July 27, 2020

Characterisation of a nucleo-adhesome.

Characterisation of a nucleo-adhesome.

Journal: Nature communications
Published: June 11, 2020

Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies.

Integrative analysis of multi-platform reverse-phase protein array data for the pharmacodynamic assessment of response to targeted therapies.

Journal: Scientific reports
Published: September 18, 2019

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer.

Journal: Gastroenterology
Published: August 08, 2019

High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1.

High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1.

Journal: EMBO reports
Published: July 02, 2019

A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High-Content Phenotypic Screen.

A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High-Content Phenotypic Screen.

Journal: Molecular cancer therapeutics
Published: March 27, 2019

Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.

Journal: Cancer research
Published: December 15, 2018

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks.

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks.

Journal: Science signaling
Published: December 07, 2017
Showing 1-12 of 30

Last Updated: 09/26/2026