Burcu Bestas
BioPharmaceuticals R&D, AstraZeneca
Goeteborg, O, Sweden
Goeteborg, O, Sweden
Last Updated: 09/26/2026
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Found 15 publications
Cell-penetrating peptide-conjugated, splice-switching oligonucleotides mitigate the phenotype in BTK/Tec double deficient X-linked agammaglobulinemia model.
Journal: RSC chemical biology
Published: December 15, 2024
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.
Journal: Nature communications
Published: January 26, 2023
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Journal: Nature communications
Published: October 03, 2022
Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing.
Journal: Nature communications
Published: September 03, 2021
Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.
Journal: Biomedicines
Published: July 20, 2021
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: July 12, 2020
The viral protein corona directs viral pathogenesis and amyloid aggregation.
Journal: Nature communications
Published: January 16, 2019
Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.
Journal: Molecular therapy. Nucleic acids
Published: September 29, 2015
Splice-correction strategies for treatment of X-linked agammaglobulinemia.
Journal: Current allergy and asthma reports
Published: February 02, 2015
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.
Journal: The Journal of clinical investigation
Published: March 21, 2014
Design and application of bispecific splice-switching oligonucleotides.
Journal: Nucleic acid therapeutics
Published: February 11, 2014
Agammaglobulinemia: causative mutations and their implications for novel therapies.
Journal: Expert review of clinical immunology
Published: November 13, 2013
Last Updated: 09/26/2026