Can Guo
Nanjing, 211198, China
Last Updated: 09/26/2026
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Found 9 publications
Design, Synthesis, and Biological Evaluation of a Cathepsin B-Activated Small Molecule-Drug Conjugate Targeting AKR1C3 to Enhance Chemotherapeutic Selectivity.
Journal: Journal of medicinal chemistry
Published: July 18, 2026
Discovery of Highly Selective AKR1C3 Inhibitors to Overcome EGFR C797S-Mediated Osimertinib Resistance in Non-Small Cell Lung Cancer.
Journal: Journal of medicinal chemistry
Published: January 30, 2026
Small Molecule-Drug Conjugates: An Emerging Drug Design Strategy for Targeted Therapeutics.
Journal: Journal of medicinal chemistry
Published: November 22, 2025
Aldo-Keto Reductase Family 1 Member B10 as a Therapeutic Frontier: Advances in Inhibitor Design and Multimodal Approaches.
Journal: Medicinal research reviews
Published: May 05, 2025
Discovery of Highly Potent AKR1C3 Inhibitors Treating Sorafenib-Resistant Hepatocellular Carcinoma.
Journal: Journal of medicinal chemistry
Published: March 27, 2025
Discovery of highly potent AKR1Cs pan-inhibitors as chemotherapeutic potentiators to restore breast cancer drug resistance.
Journal: European journal of medicinal chemistry
Published: January 07, 2025
Triazoles in Medicinal Chemistry: Physicochemical Properties, Bioisosterism, and Application.
Journal: Journal of medicinal chemistry
Published: May 03, 2024
Structural modification strategies of triazoles in anticancer drug development.
Journal: European journal of medicinal chemistry
Published: April 28, 2024
Optimizing drug-like properties of selective butyrylcholinesterase inhibitors for cognitive improvement: Enhancing aqueous solubility by disrupting molecular plane.
Journal: European journal of medicinal chemistry
Published: January 09, 2024
Showing 1-9 of 9
Last Updated: 09/26/2026