Carine Giovannangeli

Paris, France

Last Updated: 09/26/2026

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Found 31 publications

A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease.

A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease.

Journal: Blood
Published: January 03, 2025

Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish.

Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish.

Journal: Scientific reports
Published: July 25, 2024

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation.

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation.

Journal: eLife
Published: July 09, 2024

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.

Journal: Nature communications
Published: January 06, 2022

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells.

Journal: Molecular cancer
Published: November 15, 2021

Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective.

Recent Progress in Genome Editing for Gene Therapy Applications: The French Perspective.

Journal: Human gene therapy
Published: September 08, 2021

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo.

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo.

Journal: Nature communications
Published: June 22, 2021

Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells.

Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells.

Journal: Cancer research
Published: November 18, 2020

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.

Journal: Science advances
Published: July 30, 2019

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells.

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells.

Journal: PLoS genetics
Published: May 16, 2019

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models.

Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models.

Journal: Transplantation
Published: April 25, 2018

High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion.

High doses of CRISPR/Cas9 ribonucleoprotein efficiently induce gene knockout with low mosaicism in the hydrozoan Clytia hemisphaerica through microhomology-mediated deletion.

Journal: Scientific reports
Published: April 10, 2018
Showing 1-12 of 31

Last Updated: 09/26/2026