Last Updated: 09/26/2026
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Found 2 publications
Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth.
Journal: Cell cycle (Georgetown, Tex.)
Published: August 17, 2012
A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.
Journal: Carcinogenesis
Published: March 10, 2012
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Last Updated: 09/26/2026