Carla Abrahamian

Munich, BY 81675, Germany

Last Updated: 09/26/2026

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Found 16 publications

TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status.

TPC1-dependent control of endosomal pH and transferrin uptake determines cellular iron status.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 05, 2026

Common and distinct genetic features of three atherosclerotic cardiovascular diseases.

Common and distinct genetic features of three atherosclerotic cardiovascular diseases.

Journal: Atherosclerosis

Published: September 16, 2025

Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.

Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.

Journal: Frontiers in immunology

Published: July 17, 2025

Polymethoxyflavones from Kaempferia parviflora stimulate melanogenesis by blocking the TPC2 channel.

Polymethoxyflavones from Kaempferia parviflora stimulate melanogenesis by blocking the TPC2 channel.

Journal: Scientific reports

Published: May 17, 2025

Genetic Exploration of Targeting the Transient Receptor Potential Cation Channel Subfamily Member 6.

Genetic Exploration of Targeting the Transient Receptor Potential Cation Channel Subfamily Member 6.

Journal: Journal of cardiovascular pharmacology

Published: March 05, 2025

TPC2: From Blond Hair to Melanoma?

TPC2: From Blond Hair to Melanoma?

Journal: Cancers

Published: November 18, 2024

Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.

Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.

Journal: Nature communications

Published: November 23, 2023

Endolysosomal TRPML1 channel regulates cancer cell migration by altering intracellular trafficking of E-cadherin and β1-integrin.

Endolysosomal TRPML1 channel regulates cancer cell migration by altering intracellular trafficking of E-cadherin and β1-integrin.

Journal: The Journal of biological chemistry

Published: May 26, 2023

Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing.

Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing.

Journal: Journal of medicinal chemistry

Published: March 15, 2023

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.

Journal: Nature communications

Published: February 14, 2022

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.

TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.

Journal: EMBO molecular medicine

Published: November 03, 2021

Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.

Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.

Journal: Biomolecules

Published: June 16, 2021

Showing 1-12 of 16

Last Updated: 09/26/2026