Carla S. Verissimo

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 14 publications

Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli.

Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli.

Journal: Journal of medicinal chemistry

Published: August 26, 2025

Accelerating personalized medicine: miniaturized patient-derived organoid drug screening for predicting cancer treatment responses and beyond.

Accelerating personalized medicine: miniaturized patient-derived organoid drug screening for predicting cancer treatment responses and beyond.

Journal: npj biomedical innovations

Published: June 24, 2025

Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer.

Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: May 18, 2025

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response.

Journal: Journal of experimental & clinical cancer research : CR

Published: December 20, 2023

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier.

Journal: Inflammatory bowel diseases

Published: July 11, 2022

Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function.

Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function.

Journal: Journal of visualized experiments : JoVE

Published: August 16, 2021

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.

Journal: Cell reports

Published: March 02, 2021

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids.

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids.

Journal: Nature protocols

Published: June 09, 2020

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Journal: eLife

Published: June 05, 2016

Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

Journal: PloS one

Published: March 24, 2013

Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: implications for neurogenesis.

Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: implications for neurogenesis.

Journal: The Journal of comparative neurology

Published: May 19, 2012

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

Journal: The Journal of pharmacology and experimental therapeutics

Published: April 12, 2012

Showing 1-12 of 14

Last Updated: 09/26/2026