Carles Galdeano

Barcelona, CT, Spain

Last Updated: 09/26/2026

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Found 30 publications

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening.

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening.

Journal: Chembiochem : a European journal of chemical biology

Published: March 27, 2026

Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity.

Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of β-Amyloid and Tau Aggregation with Anticholinesterase Activity.

Journal: Biomolecules

Published: March 02, 2026

Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain.

Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: October 23, 2025

Water Networks as Hydrophobic Recognition Motifs in Proteins.

Water Networks as Hydrophobic Recognition Motifs in Proteins.

Journal: Angewandte Chemie (International ed. in English)

Published: September 25, 2025

Characterization of Ligand Binding in Human Serum Albumin from Atomistic Energy Transfer Simulations.

Characterization of Ligand Binding in Human Serum Albumin from Atomistic Energy Transfer Simulations.

Journal: Small methods

Published: September 10, 2025

Discovering Uncharted Binding Pockets on E3 Ligases Leads to the Identification of FBW7 Allosteric Modulators.

Discovering Uncharted Binding Pockets on E3 Ligases Leads to the Identification of FBW7 Allosteric Modulators.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 04, 2025

A bottom-up approach to find lead compounds in expansive chemical spaces.

A bottom-up approach to find lead compounds in expansive chemical spaces.

Journal: Communications chemistry

Published: January 28, 2025

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome.

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome.

Journal: Cell communication and signaling : CCS

Published: October 25, 2024

Drug Discovery Approaches to Target E3 Ligases.

Drug Discovery Approaches to Target E3 Ligases.

Journal: Chembiochem : a European journal of chemical biology

Published: August 07, 2024

Proximity-Induced Pharmacology for Amyloid-Related Diseases.

Proximity-Induced Pharmacology for Amyloid-Related Diseases.

Journal: Cells

Published: January 30, 2024

Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.

Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 26, 2023

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis.

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 11, 2022

Showing 1-12 of 30

Last Updated: 09/26/2026