Carlo Heirman

Niel, VLG, Belgium

Last Updated: 09/26/2026

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Found 50 publications

Autoantigen mRNA-LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity.

Autoantigen mRNA-LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: March 06, 2026

mRNA-LNP COVID-19 Vaccine Lipids Induce Complement Activation and Production of Proinflammatory Cytokines: Mechanisms, Effects of Complement Inhibitors, and Relevance to Adverse Reactions.

mRNA-LNP COVID-19 Vaccine Lipids Induce Complement Activation and Production of Proinflammatory Cytokines: Mechanisms, Effects of Complement Inhibitors, and Relevance to Adverse Reactions.

Journal: International journal of molecular sciences

Published: February 08, 2024

A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases.

A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases.

Journal: Cancer immunology, immunotherapy : CII

Published: October 28, 2019

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice.

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice.

Journal: Journal of translational medicine

Published: March 19, 2019

Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection.

Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection.

Journal: AIDS (London, England)

Published: October 06, 2018

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.

Journal: ACS nano

Published: September 27, 2018

GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma.

GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma.

Journal: International journal of cancer

Published: September 12, 2018

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages.

Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: September 04, 2018

The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent.

The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: March 08, 2018

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation.

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation.

Journal: Diabetologia

Published: December 12, 2017

Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy.

Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy.

Journal: International journal of cancer

Published: August 25, 2017

Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression.

Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression.

Journal: Cancer research

Published: May 31, 2017

Showing 1-12 of 50

Last Updated: 09/26/2026