Carlos M. Dominguez-Diaz

Bizkaia Technology Park
Derio, PV, Spain

Last Updated: 09/26/2026

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Found 15 publications

Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains.

Regulated coexpression of PrP from different species in mice impacts the replication and host range properties of prion strains.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 26, 2025

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains.

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains.

Journal: Brain pathology (Zurich, Switzerland)

Published: September 09, 2025

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness.

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness.

Journal: Acta neuropathologica communications

Published: August 26, 2025

Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties.

Spontaneous generation of diverse recombinant prion strains: sulfated glycan cofactors facilitate strain emergence but do not determine specific strain properties.

Journal: Acta neuropathologica communications

Published: June 12, 2025

Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity.

Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity.

Journal: Neurobiology of disease

Published: April 10, 2025

A comprehensive phylogeny of mammalian PRNP gene reveals no influence of prion misfolding propensity on the evolution of this gene.

A comprehensive phylogeny of mammalian PRNP gene reveals no influence of prion misfolding propensity on the evolution of this gene.

Journal: PLoS pathogens

Published: February 14, 2025

Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions.

Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions.

Journal: PLoS pathogens

Published: October 04, 2024

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions.

A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions.

Journal: Nature communications

Published: October 13, 2023

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.

Journal: Acta neuropathologica communications

Published: June 29, 2023

Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.

Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model.

Journal: Acta neuropathologica communications

Published: September 16, 2022

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy.

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy.

Journal: PLoS pathogens

Published: April 28, 2022

Description of the first Spanish case of Gerstmann-Sträussler-Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization.

Description of the first Spanish case of Gerstmann-Sträussler-Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization.

Journal: Journal of neurology

Published: November 11, 2021

Showing 1-12 of 15

Last Updated: 09/26/2026