Carmen Abate

Via Orabona 4
Bari, 70125, Italy

Last Updated: 09/26/2026

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Found 76 publications

Retraction Note: Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor.

Retraction Note: Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor.

Journal: BMC cancer

Published: August 14, 2026

MD Simulations of Human Sigma-1 Receptor Trimer Uncover Cholesterol-Dependent Stabilization and Ligand-Specific Dynamics.

MD Simulations of Human Sigma-1 Receptor Trimer Uncover Cholesterol-Dependent Stabilization and Ligand-Specific Dynamics.

Journal: Journal of chemical information and modeling

Published: June 01, 2026

A Novel Class of "Super-Strained" Spiro Heterocycles: Gateway to 1-Azaspiro[3.3]heptane Derivatives, and Biological Validation.

A Novel Class of "Super-Strained" Spiro Heterocycles: Gateway to 1-Azaspiro[3.3]heptane Derivatives, and Biological Validation.

Journal: Angewandte Chemie (International ed. in English)

Published: March 24, 2026

Unveiling the molecular crosstalk between the purinergic P2X7 receptor and cannabinoid subtype 2 receptor in human microglial HMC3 cells: New insights for multitarget therapies in neuroinflammation.

Unveiling the molecular crosstalk between the purinergic P2X7 receptor and cannabinoid subtype 2 receptor in human microglial HMC3 cells: New insights for multitarget therapies in neuroinflammation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 06, 2026

Development of Second-Generation Phenoxyethylpiperidines as Potent Sigma-1 Receptor Agonists with Neuroprotective Potential for Alzheimer's Disease.

Development of Second-Generation Phenoxyethylpiperidines as Potent Sigma-1 Receptor Agonists with Neuroprotective Potential for Alzheimer's Disease.

Journal: Journal of medicinal chemistry

Published: February 05, 2026

Correction to "First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer".

Correction to "First-In-Class Thiosemicarbazone Metal Complexes Targeting the Sigma-2 Receptor (S2R) as an Innovative Strategy against Pancreatic Cancer".

Journal: Journal of medicinal chemistry

Published: January 16, 2026

Zervimesine, a Small Sigma‑2 Receptor Selective Modulator for Alzheimer's Disease.

Zervimesine, a Small Sigma‑2 Receptor Selective Modulator for Alzheimer's Disease.

Journal: ACS medicinal chemistry letters

Published: October 28, 2025

Pridopidine, a Potent and Selective Therapeutic Sigma-1 Receptor (S1R) Agonist for Treating Neurodegenerative Diseases.

Pridopidine, a Potent and Selective Therapeutic Sigma-1 Receptor (S1R) Agonist for Treating Neurodegenerative Diseases.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 27, 2025

A Full-Spectrum Evaluation of Sigma-1 Receptor (S1R) Positron Emission Tomography (PET) Radioligands from Binding Affinity to Clinical Imaging.

A Full-Spectrum Evaluation of Sigma-1 Receptor (S1R) Positron Emission Tomography (PET) Radioligands from Binding Affinity to Clinical Imaging.

Journal: Molecules (Basel, Switzerland)

Published: October 09, 2025

Healthy BRCA1/2 mutation carriers exhibit a pre-CAF signature and altered epithelial marker expression in breast tissue.

Healthy BRCA1/2 mutation carriers exhibit a pre-CAF signature and altered epithelial marker expression in breast tissue.

Journal: Scientific reports

Published: May 27, 2025

CC48 a new CB2R agonist/FAAH inhibitor dual drug blocks gastric cancer progression and overcomes paclitaxel resistance.

CC48 a new CB2R agonist/FAAH inhibitor dual drug blocks gastric cancer progression and overcomes paclitaxel resistance.

Journal: Journal of experimental & clinical cancer research : CR

Published: April 09, 2025

Sigma-2 Receptor Antagonism Enhances the Neuroprotective Effects of Pridopidine, a Sigma-1 Receptor Agonist, in Huntington's Disease.

Sigma-2 Receptor Antagonism Enhances the Neuroprotective Effects of Pridopidine, a Sigma-1 Receptor Agonist, in Huntington's Disease.

Journal: Molecular neurobiology

Published: February 19, 2025

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Last Updated: 09/26/2026