Carolina Colliva

S.r.l, Via Giovine Italia 1
Solomeo, 06073, Italy

Last Updated: 09/26/2026

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Found 17 publications

Structure-Based Discovery of Obeticholic Acid Derivatives as Novel Farnesoid X Receptor Partial Agonists with Improved Selectivity and Reduced Off-Target Effects.

Structure-Based Discovery of Obeticholic Acid Derivatives as Novel Farnesoid X Receptor Partial Agonists with Improved Selectivity and Reduced Off-Target Effects.

Journal: ChemMedChem

Published: October 24, 2025

Tryptophan pathway profiling in multiple sclerosis patients treated with ocrelizumab.

Tryptophan pathway profiling in multiple sclerosis patients treated with ocrelizumab.

Journal: Frontiers in immunology

Published: March 31, 2025

Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization.

Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization.

Journal: European journal of medicinal chemistry

Published: March 27, 2024

Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.

Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 21, 2022

Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies.

Probing Fluorinated Motifs onto Dual AChE-MAO B Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Early-ADME Studies.

Journal: Journal of medicinal chemistry

Published: February 23, 2022

Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.

Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.

Journal: Immunity

Published: August 31, 2021

Ablation of liver Fxr results in an increased colonic mucus barrier in mice.

Ablation of liver Fxr results in an increased colonic mucus barrier in mice.

Journal: JHEP reports : innovation in hepatology

Published: June 01, 2021

Vortioxetine Prevents Lipopolysaccharide-Induced Memory Impairment Without Inhibiting the Initial Inflammatory Cascade.

Vortioxetine Prevents Lipopolysaccharide-Induced Memory Impairment Without Inhibiting the Initial Inflammatory Cascade.

Journal: Frontiers in pharmacology

Published: September 08, 2020

Lymnaea stagnalis as model for translational neuroscience research: From pond to bench.

Lymnaea stagnalis as model for translational neuroscience research: From pond to bench.

Journal: Neuroscience and biobehavioral reviews

Published: July 26, 2019

Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification.

Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification.

Journal: European journal of medicinal chemistry

Published: November 02, 2017

Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.

Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.

Journal: Journal of medicinal chemistry

Published: September 23, 2016

Semisynthetic bile acid FXR and TGR5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.

Semisynthetic bile acid FXR and TGR5 agonists: physicochemical properties, pharmacokinetics, and metabolism in the rat.

Journal: The Journal of pharmacology and experimental therapeutics

Published: May 03, 2014

Showing 1-12 of 17

Last Updated: 09/26/2026