Carolina Zarzalejo-Sanchez
Barcelona, CT 08028, Spain
Last Updated: 09/26/2026
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Found 9 publications
The synthetic landscape of cereblon (CRBN) binders: from thalidomide to emerging chemotypes.
Journal: Chemical Society reviews
Published: July 14, 2026
Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule.
Journal: Science advances
Published: February 27, 2026
Targeted KRASG12V Degradation In Vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis.
Journal: Cancer research
Published: November 12, 2025
Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis.
Journal: Cancer research
Published: November 12, 2025
TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages.
Journal: Nature genetics
Published: August 16, 2024
New Potent Inhibitor of Transforming Growth Factor-Beta (TGFβ) Signaling that is Efficacious against Microsatellite Stable Colorectal Cancer Metastasis in Combination with Immune Checkpoint Therapy in Mice.
Journal: ACS pharmacology & translational science
Published: June 20, 2024
Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders.
Journal: Angewandte Chemie (International ed. in English)
Published: November 05, 2023
Rational optimization of a transcription factor activation domain inhibitor.
Journal: Nature structural & molecular biology
Published: November 21, 2022
Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation.
Journal: European journal of medicinal chemistry
Published: March 06, 2020
Showing 1-9 of 9
Last Updated: 09/26/2026