Caroline P. Berthier

Paris, France

Last Updated: 09/26/2026

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Found 11 publications

Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.

Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function.

Journal: Cancer discovery
Published: April 16, 2023

Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML).

Biological Effects of BET Inhibition by OTX015 (MK-8628) and JQ1 in NPM1-Mutated (NPM1c) Acute Myeloid Leukemia (AML).

Journal: Biomedicines
Published: September 07, 2021

Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.

Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy.

Journal: Cancer discovery
Published: February 08, 2021

A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia.

A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia.

Journal: Haematologica
Published: October 24, 2020

Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML.

Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML.

Journal: Leukemia
Published: September 30, 2020

FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.

FLT3-ITD impedes retinoic acid, but not arsenic, responses in murine acute promyelocytic leukemias.

Journal: Blood
Published: July 27, 2018

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia.

Journal: Nature communications
Published: July 17, 2017

Detection of Protein SUMOylation In Situ by Proximity Ligation Assays.

Detection of Protein SUMOylation In Situ by Proximity Ligation Assays.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: September 16, 2016

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.

Journal: Cancer
Published: August 24, 2016

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells.

Journal: Blood
Published: November 18, 2014

Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.

Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.

Journal: The Journal of cell biology
Published: March 19, 2014
Showing 1-11 of 11

Last Updated: 09/26/2026