Last Updated: 09/26/2026
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Found 72 publications
Correction to "Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates".
Journal: Journal of medicinal chemistry
Published: September 26, 2025
Isoindolinone-Based PET Tracers for Imaging Mutant Huntingtin Aggregates.
Journal: Journal of medicinal chemistry
Published: July 07, 2025
In Vivo PET Imaging of [18F]CHDI-385, a Radioligand for Mutant Huntingtin Aggregates in a Mouse Model of Huntington Disease.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Published: June 19, 2025
Preclinical evaluation of [11C]CHDI-009R for quantification of mutant huntingtin aggregates.
Journal: Journal of molecular medicine (Berlin, Germany)
Published: June 04, 2025
Post-translational modifications of huntingtin's N17 region: implications for self-association and membrane binding.
Journal: Biochimica et biophysica acta. Molecular basis of disease
Published: April 01, 2025
Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors.
Journal: Bioorganic & medicinal chemistry letters
Published: February 19, 2025
Lack of Evidence for Kynurenine Pathway Dysfunction in Huntington's Disease: CSF and Plasma Analyses from the HDClarity Study.
Journal: Journal of Huntington's disease
Published: February 05, 2025
Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition.
Journal: Nucleic acids research
Published: November 04, 2024
Preclinical evaluation of the novel [18F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease.
Journal: European journal of nuclear medicine and molecular imaging
Published: May 22, 2024
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Journal: Journal of medicinal chemistry
Published: September 15, 2023
Validation of LC-MS/MS methods for quantitative analysis of kynurenine pathway metabolites in human plasma and cerebrospinal fluid.
Journal: Bioanalysis
Published: May 12, 2023
IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway.
Journal: Life science alliance
Published: February 22, 2023
Last Updated: 09/26/2026