Chai A. Ng

405 Liverpool Street
Darlinghurst, NSW 2010, Australia

Last Updated: 09/26/2026

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Found 11 publications

Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance.

Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance.

Journal: Human molecular genetics

Published: August 23, 2022

The S1 helix critically regulates the finely tuned gating of Kv11.1 channels.

The S1 helix critically regulates the finely tuned gating of Kv11.1 channels.

Journal: The Journal of biological chemistry

Published: January 31, 2017

Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations.

Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations.

Journal: The Journal of physiology

Published: October 30, 2015

Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.

Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.

Journal: The Journal of biological chemistry

Published: July 31, 2014

Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.

Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.

Journal: The Journal of biological chemistry

Published: April 04, 2014

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

Journal: The Journal of general physiology

Published: August 28, 2013

Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions.

Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions.

Journal: The Biochemical journal

Published: June 01, 2013

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

Journal: PloS one

Published: April 29, 2013

Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.

Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.

Journal: The Journal of biological chemistry

Published: March 09, 2013

Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels.

Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels.

Journal: The Journal of general physiology

Published: August 15, 2012

Insights into hERG K+ channel structure and function from NMR studies.

Insights into hERG K+ channel structure and function from NMR studies.

Journal: European biophysics journal : EBJ

Published: December 28, 2011

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Last Updated: 09/26/2026