Chang H. Lee

Seoul, Republic of Korea

Last Updated: 09/26/2026

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Found 31 publications

Spatial autophagy failure as a pharmacodynamic endpoint for autophagy-targeted dermatological interventions.

Spatial autophagy failure as a pharmacodynamic endpoint for autophagy-targeted dermatological interventions.

Journal: Pharmacological research
Published: July 03, 2026

Natural products, artificial intelligence, and the future of anti-aging pharmacology: A human-centered call to action.

Natural products, artificial intelligence, and the future of anti-aging pharmacology: A human-centered call to action.

Journal: Pharmacological research
Published: September 07, 2025

Research Progress on Anti-Aging with Natural Products: From Pathway Modulation to AI-Driven Discovery.

Research Progress on Anti-Aging with Natural Products: From Pathway Modulation to AI-Driven Discovery.

Journal: Biomolecules
Published: August 26, 2025

From prevalence to practice: Integrating dietary energy density into meta-analytic research on obesity in older adults.

From prevalence to practice: Integrating dietary energy density into meta-analytic research on obesity in older adults.

Journal: Public health in practice (Oxford, England)
Published: August 05, 2025

Procyanidin A2, a polyphenol autophagy-enhancer, ameliorates hyperglycemia through multifaceted insulin-related mechanisms.

Procyanidin A2, a polyphenol autophagy-enhancer, ameliorates hyperglycemia through multifaceted insulin-related mechanisms.

Journal: Scientific reports
Published: June 24, 2025

Synergistic effects of Rhynchosia nulubilis and Polygonum multiflorum extract combination on cell proliferation via targeting IGFBP-1 & NT-3 and cytotoxicity suppression in testosterone-induced human dermal papilla cells.

Synergistic effects of Rhynchosia nulubilis and Polygonum multiflorum extract combination on cell proliferation via targeting IGFBP-1 & NT-3 and cytotoxicity suppression in testosterone-induced human dermal papilla cells.

Journal: PloS one
Published: October 12, 2024

Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding.

Giant Centella asiatica, a novel cultivar rich in madecassoside and asiaticoside, suppresses α‑melanocyte‑stimulating hormone‑induced melanogenesis through MC1R binding.

Journal: International journal of molecular medicine
Published: July 19, 2024

Catechin and flavonoid glycosides from the Ulmus genus: Exploring their nutritional pharmacology and therapeutic potential in osteoporosis and inflammatory conditions.

Catechin and flavonoid glycosides from the Ulmus genus: Exploring their nutritional pharmacology and therapeutic potential in osteoporosis and inflammatory conditions.

Journal: Fitoterapia
Published: June 09, 2024

Fermented Yak-Kong using Bifidobacterium animalis derived from Korean infant intestine effectively relieves muscle atrophy in an aging mouse model.

Fermented Yak-Kong using Bifidobacterium animalis derived from Korean infant intestine effectively relieves muscle atrophy in an aging mouse model.

Journal: Food & function
Published: May 30, 2024

RSM- and ANN-Based Multifrequency Ultrasonic Extraction of Polyphenol-Rich Sargassum horneri Extracts Exerting Antioxidative Activity via the Regulation of MAPK/Nrf2/HO-1 Machinery.

RSM- and ANN-Based Multifrequency Ultrasonic Extraction of Polyphenol-Rich Sargassum horneri Extracts Exerting Antioxidative Activity via the Regulation of MAPK/Nrf2/HO-1 Machinery.

Journal: Antioxidants (Basel, Switzerland)
Published: April 09, 2024

Photoprotective activities of Capsosiphon fulvescens in UVB-induced SKH-1 mice and human keratinocytes.

Photoprotective activities of Capsosiphon fulvescens in UVB-induced SKH-1 mice and human keratinocytes.

Journal: Journal of food science
Published: March 27, 2024

γ-Mangosteen, an autophagy enhancer, prevents skin-aging via activating KEAP1/NRF2 signaling and downregulating MAPKs/AP-1/NF-κB-mediated MMPs.

γ-Mangosteen, an autophagy enhancer, prevents skin-aging via activating KEAP1/NRF2 signaling and downregulating MAPKs/AP-1/NF-κB-mediated MMPs.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Published: October 19, 2023
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Last Updated: 09/26/2026