Chang-run H. Guo

Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 29 publications

A subset of endogenous P2X5 transcripts encodes ATP-sensitive receptor isoforms.

A subset of endogenous P2X5 transcripts encodes ATP-sensitive receptor isoforms.

Journal: Science bulletin

Published: March 28, 2026

Structure of the human P2X3 receptor reveals the basis for subtype-selective inhibition by sivopixant.

Structure of the human P2X3 receptor reveals the basis for subtype-selective inhibition by sivopixant.

Journal: PLoS biology

Published: January 29, 2026

The clinical study of azacitidine and lenalidomide combination in myelodysplastic neoplasm patients with TP53 mutations

The clinical study of azacitidine and lenalidomide combination in myelodysplastic neoplasm patients with TP53 mutations

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

Published: December 17, 2025

Understanding interspecies drug response variations between human and rodent P2X7 receptors.

Understanding interspecies drug response variations between human and rodent P2X7 receptors.

Journal: Nature communications

Published: September 29, 2024

Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.

Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.

Journal: Science (New York, N.Y.)

Published: September 26, 2024

Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists.

Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists.

Journal: eLife

Published: April 05, 2024

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family.

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family.

Journal: Computational and structural biotechnology journal

Published: May 02, 2023

Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.

Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.

Journal: Nature communications

Published: November 02, 2022

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.

Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.

Journal: Frontiers in molecular biosciences

Published: April 21, 2022

P2X3-selective mechanism of Gefapixant, a drug candidate for the treatment of refractory chronic cough.

P2X3-selective mechanism of Gefapixant, a drug candidate for the treatment of refractory chronic cough.

Journal: Computational and structural biotechnology journal

Published: November 03, 2021

Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.

Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.

Journal: Frontiers in pharmacology

Published: September 19, 2021

The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors.

The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors.

Journal: The Journal of biological chemistry

Published: September 10, 2021

Showing 1-12 of 29

Last Updated: 09/26/2026