Chang Wang

State Key Laboratory Of Materials For Integrated Circuits
Shanghai, 200050, China

Last Updated: 09/26/2026

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Found 14 publications

Gold nanoparticle-modified single-walled carbon nanotube terahertz metasurface for ultrasensitive sensing of trace proteins.

Gold nanoparticle-modified single-walled carbon nanotube terahertz metasurface for ultrasensitive sensing of trace proteins.

Journal: Talanta

Published: November 20, 2024

Integrative proteogenomic and pharmacological landscape of acute myeloid leukaemia.

Integrative proteogenomic and pharmacological landscape of acute myeloid leukaemia.

Journal: Science bulletin

Published: June 24, 2024

Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities.

Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities.

Journal: Journal of medicinal chemistry

Published: August 16, 2023

Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3Kα inhibitors via virtual screening and docking-based structure optimization.

Discovery of 4-oxo-4,5-dihydropyrazolo[1,5-a]quinoxaline-7-carboxamide derivatives as PI3Kα inhibitors via virtual screening and docking-based structure optimization.

Journal: Bioorganic & medicinal chemistry

Published: January 21, 2023

Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors.

Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors.

Journal: ChemMedChem

Published: December 05, 2022

Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors.

Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: November 30, 2022

Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors.

Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors.

Journal: Bioorganic & medicinal chemistry

Published: November 29, 2022

Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia.

Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia.

Journal: Leukemia

Published: November 16, 2022

Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia.

Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia.

Journal: Nature communications

Published: May 09, 2022

Theoretical Analysis of Terahertz Frequency Multiplier Based on Semiconductor Superlattices.

Theoretical Analysis of Terahertz Frequency Multiplier Based on Semiconductor Superlattices.

Journal: Nanomaterials (Basel, Switzerland)

Published: March 01, 2022

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT.

Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT.

Journal: Journal of medicinal chemistry

Published: February 09, 2022

Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile.

Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile.

Journal: Journal of medicinal chemistry

Published: October 19, 2021

Showing 1-12 of 14

Last Updated: 09/26/2026