Changjie Wu

Guangdong Provincial Key Laboratory Of Gastroenterology
Guangzhou, 510515, China

Last Updated: 09/26/2026

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Found 18 publications

ARID1A deficiency activates OSM-STAT3 axis in endometrial cancer, creating vulnerability to JAK/STAT3 inhibition.

ARID1A deficiency activates OSM-STAT3 axis in endometrial cancer, creating vulnerability to JAK/STAT3 inhibition.

Journal: International journal of biological sciences

Published: November 28, 2025

Targeting miR-4653-3p/SLC25A51/SIRT3 axis to induce synthetic lethality in ARID1A-deficient colorectal cancer via blockade of DNA repair.

Targeting miR-4653-3p/SLC25A51/SIRT3 axis to induce synthetic lethality in ARID1A-deficient colorectal cancer via blockade of DNA repair.

Journal: Journal of translational medicine

Published: September 02, 2025

Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine.

Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine.

Journal: Cell death discovery

Published: May 25, 2025

FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.

FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.

Journal: NPJ precision oncology

Published: February 14, 2025

MAP4 phosphorylation induced by ARID1A loss sensitizes colorectal cancer cells to EMP.

MAP4 phosphorylation induced by ARID1A loss sensitizes colorectal cancer cells to EMP.

Journal: Cell death & disease

Published: November 07, 2024

ARID1A loss sensitizes colorectal cancer cells to floxuridine.

ARID1A loss sensitizes colorectal cancer cells to floxuridine.

Journal: Neoplasia (New York, N.Y.)

Published: August 06, 2024

ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis.

ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis.

Journal: Cell death and differentiation

Published: July 02, 2024

Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.

Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer.

Journal: Journal of translational medicine

Published: February 20, 2024

Therapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis).

Therapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis).

Journal: Cell death & disease

Published: January 16, 2024

Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer.

Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer.

Journal: Cellular and molecular life sciences : CMLS

Published: August 13, 2023

LIMK1 m6A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.

LIMK1 m6A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation.

Journal: Cancer letters

Published: July 07, 2023

METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.

METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer.

Journal: Cell death & disease

Published: August 29, 2022

Showing 1-12 of 18

Last Updated: 09/26/2026