Chao-chien C. Chang

TPQ, Taiwan

Last Updated: 09/26/2026

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Found 45 publications

Ferulenol, a Prenylated Coumarin, Suppresses Collagen-Induced Platelet Activation via PLCγ2-Mediated cPLA2 Signaling in Humans.

Ferulenol, a Prenylated Coumarin, Suppresses Collagen-Induced Platelet Activation via PLCγ2-Mediated cPLA2 Signaling in Humans.

Journal: Die Pharmazie

Published: April 01, 2026

Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans.

Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans.

Journal: Biomolecules

Published: September 30, 2025

Distinct Thromboxane A₂-Dependent Pathways Regulate Arachidonic Acid-Triggered VASP Phosphorylation at Ser239 and Ser157 in Human Platelets: Real-Time Visualization Reveals Superior Antithrombotic Efficacy by Targeting Thromboxane A₂ Signaling over Cyclooxygenase Inhibition.

Distinct Thromboxane A₂-Dependent Pathways Regulate Arachidonic Acid-Triggered VASP Phosphorylation at Ser239 and Ser157 in Human Platelets: Real-Time Visualization Reveals Superior Antithrombotic Efficacy by Targeting Thromboxane A₂ Signaling over Cyclooxygenase Inhibition.

Journal: Journal of cellular physiology

Published: August 15, 2025

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway.

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway.

Journal: Molecular medicine reports

Published: July 06, 2025

Effects of metformin treatment on the risk of acute myocardial infarction.

Effects of metformin treatment on the risk of acute myocardial infarction.

Journal: Scientific reports

Published: December 08, 2024

Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets.

Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets.

Journal: Chinese medicine

Published: February 01, 2023

Garcinol acts as a novel integrin αIIbβ3 inhibitor in human platelets.

Garcinol acts as a novel integrin αIIbβ3 inhibitor in human platelets.

Journal: Life sciences

Published: February 01, 2023

Effects of treatment with clopidogrel with or without proton pump inhibitor omeprazole on the risk of ischemic stroke: a nationwide cohort study.

Effects of treatment with clopidogrel with or without proton pump inhibitor omeprazole on the risk of ischemic stroke: a nationwide cohort study.

Journal: Scientific reports

Published: January 15, 2023

Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration.

Targeting MAPK/NF-κB Pathways in Anti-Inflammatory Potential of Rutaecarpine: Impact on Src/FAK-Mediated Macrophage Migration.

Journal: International journal of molecular sciences

Published: November 22, 2021

Participation of lipopolysaccharide in hyperplasic adipose expansion: Involvement of NADPH oxidase/ROS/p42/p44 MAPK-dependent Cyclooxygenase-2.

Participation of lipopolysaccharide in hyperplasic adipose expansion: Involvement of NADPH oxidase/ROS/p42/p44 MAPK-dependent Cyclooxygenase-2.

Journal: Journal of cellular and molecular medicine

Published: October 31, 2021

Rutaecarpine, an Alkaloid from Evodia rutaecarpa, Can Prevent Platelet Activation in Humans and Reduce Microvascular Thrombosis in Mice: Crucial Role of the PI3K/Akt/GSK3β Signal Axis through a Cyclic Nucleotides/VASP-Independent Mechanism.

Rutaecarpine, an Alkaloid from Evodia rutaecarpa, Can Prevent Platelet Activation in Humans and Reduce Microvascular Thrombosis in Mice: Crucial Role of the PI3K/Akt/GSK3β Signal Axis through a Cyclic Nucleotides/VASP-Independent Mechanism.

Journal: International journal of molecular sciences

Published: August 19, 2021

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism.

Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism.

Journal: Autophagy

Published: March 22, 2021

Showing 1-12 of 45

Last Updated: 09/26/2026