Charles E. Assmann

1000 Roraima Avenue
Santa Maria, RS 97105900, Brazil

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 63 publications

Modulation of the PI3K/AKT/mTOR and AMPK/TSC2/mTOR Pathways by N-Acetyl-L-Cysteine as a Protector of Embryonic Bodies from the Toxic Effect of Methylmercury.

Modulation of the PI3K/AKT/mTOR and AMPK/TSC2/mTOR Pathways by N-Acetyl-L-Cysteine as a Protector of Embryonic Bodies from the Toxic Effect of Methylmercury.

Journal: Brain sciences

Published: March 13, 2026

Targeting the gut-immune-brain axis: pharmacological insights from depression in inflammatory bowel disease.

Targeting the gut-immune-brain axis: pharmacological insights from depression in inflammatory bowel disease.

Journal: Frontiers in pharmacology

Published: January 21, 2026

Resveratrol as a potential natural compound to ameliorate cognitive impairment in aluminum-exposed mice: impacts on behavior, purinergic system, and brain inflammation.

Resveratrol as a potential natural compound to ameliorate cognitive impairment in aluminum-exposed mice: impacts on behavior, purinergic system, and brain inflammation.

Journal: Metabolic brain disease

Published: October 13, 2025

Capsaicin suppresses LPS-induced inflammatory responses via NLRP3/CASP-1/IL-1β axis and purinergic pathways in BV-2 microglial cells.

Capsaicin suppresses LPS-induced inflammatory responses via NLRP3/CASP-1/IL-1β axis and purinergic pathways in BV-2 microglial cells.

Journal: Purinergic signalling

Published: August 14, 2025

Cytotoxic and immunotoxic profile of HgCl2 involves alterations in purinergic signaling through the P2X7/NLRP3/CASP-1/IL-1β pathway: An in vitro study using human blood immune cells.

Cytotoxic and immunotoxic profile of HgCl2 involves alterations in purinergic signaling through the P2X7/NLRP3/CASP-1/IL-1β pathway: An in vitro study using human blood immune cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: June 06, 2025

Quercetin and Tranylcypromine Improve Memory, Behavioral Performance, and Cholinergic Function in Male Rats Subjected to Chronic Restraint Stress.

Quercetin and Tranylcypromine Improve Memory, Behavioral Performance, and Cholinergic Function in Male Rats Subjected to Chronic Restraint Stress.

Journal: Brain sciences

Published: June 03, 2025

Resveratrol Alleviates Inflammatory Response Through P2X7/NLRP3 Signaling Pathway: In Silico and In Vitro Evidence from Activated Microglia.

Resveratrol Alleviates Inflammatory Response Through P2X7/NLRP3 Signaling Pathway: In Silico and In Vitro Evidence from Activated Microglia.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: May 20, 2025

Neuroprotective effects of a thiazolidin-4-one against lipopolysaccharide-induced neuroinflammation in mice: impact on memory, antioxidant and cholinergic systems, and glial reactivity.

Neuroprotective effects of a thiazolidin-4-one against lipopolysaccharide-induced neuroinflammation in mice: impact on memory, antioxidant and cholinergic systems, and glial reactivity.

Journal: European journal of pharmacology

Published: February 26, 2025

The Neuroprotective Role of A2A Adenosine Purinoceptor Modulation as a Strategy Against Glioblastoma.

The Neuroprotective Role of A2A Adenosine Purinoceptor Modulation as a Strategy Against Glioblastoma.

Journal: Brain sciences

Published: December 01, 2024

Blackcurrant (Ribes nigrum L.) and Its Association with Donepezil Restore Cognitive Impairment, Suppress Oxidative Stress and Pro-inflammatory Responses, and Improve Purinergic Signaling in a Scopolamine-Induced Amnesia Model in Mice.

Blackcurrant (Ribes nigrum L.) and Its Association with Donepezil Restore Cognitive Impairment, Suppress Oxidative Stress and Pro-inflammatory Responses, and Improve Purinergic Signaling in a Scopolamine-Induced Amnesia Model in Mice.

Journal: Neurochemical research

Published: October 09, 2024

Effects of Free and Nanoencapsulated Benznidazole in Acute Trypanosoma cruzi Infection: Role of Cholinergic Pathway and Redox Status.

Effects of Free and Nanoencapsulated Benznidazole in Acute Trypanosoma cruzi Infection: Role of Cholinergic Pathway and Redox Status.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: September 16, 2024

Blackcurrant (Ribes nigrum L.) improves cholinergic signaling and protects against chronic Scopolamine-induced memory impairment in mice.

Blackcurrant (Ribes nigrum L.) improves cholinergic signaling and protects against chronic Scopolamine-induced memory impairment in mice.

Journal: Journal of psychopharmacology (Oxford, England)

Published: September 12, 2024

Showing 1-12 of 63

Last Updated: 09/26/2026