Charles L. Sawyers

Hematology | Oncology

1275 York Ave
New York, NY 10065

Last Updated: 09/26/2026

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Found 133 publications

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development.

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development.

Journal: bioRxiv : the preprint server for biology

Published: August 20, 2026

Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer.

Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer.

Journal: Nature

Published: July 01, 2026

Dependencies in heterogeneous, lineage plastic patient-derived prostate cancer organoids revealed through integrated single-cell multiomics and CRISPR screening.

Dependencies in heterogeneous, lineage plastic patient-derived prostate cancer organoids revealed through integrated single-cell multiomics and CRISPR screening.

Journal: bioRxiv : the preprint server for biology

Published: May 18, 2026

Dependencies in heterogeneous, lineage plastic patient-derived prostate cancer organoids revealed through integrated single-cell multiomics and CRISPR screening.

Dependencies in heterogeneous, lineage plastic patient-derived prostate cancer organoids revealed through integrated single-cell multiomics and CRISPR screening.

Journal: bioRxiv : the preprint server for biology

Published: May 18, 2026

MYC pathway reprogramming through a TIP60 coactivator switch in neuroendocrine lineage transition in prostate cancer.

MYC pathway reprogramming through a TIP60 coactivator switch in neuroendocrine lineage transition in prostate cancer.

Journal: bioRxiv : the preprint server for biology

Published: May 18, 2026

Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival.

Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival.

Journal: Cancer discovery

Published: February 25, 2026

Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD.

Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD.

Journal: bioRxiv : the preprint server for biology

Published: January 09, 2026

Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival in a pandemic.

Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival in a pandemic.

Journal: medRxiv : the preprint server for health sciences

Published: December 03, 2025

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

Journal: Cell reports

Published: May 05, 2025

Targeting Tumor Microenvironment-Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer.

Targeting Tumor Microenvironment-Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer.

Journal: Molecular cancer therapeutics

Published: May 05, 2025

Stochastically Emergent Tumors offer in vivo whole genome interrogation of cancer evolution from non-malignant precursors.

Stochastically Emergent Tumors offer in vivo whole genome interrogation of cancer evolution from non-malignant precursors.

Journal: bioRxiv : the preprint server for biology

Published: April 01, 2025

Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers.

Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers.

Journal: Science advances

Published: February 07, 2025

Showing 1-12 of 133

Last Updated: 09/26/2026