Last Updated: 09/26/2026
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Found 11 publications
Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants.
Journal: International clinical psychopharmacology
Published: February 27, 2026
Reasons for Maintaining the Classification of Esmethadone as an Investigational Uncompetitive NMDAR Antagonist Rapid Antidepressant: Reply to Ferré and Michaelides.
Journal: The Journal of clinical psychiatry
Published: September 18, 2025
Long-Term Safety and Efficacy of Esmethadone in Patients With Major Depressive Disorder: Findings From a 12-Month Open-Label Study.
Journal: The Journal of clinical psychiatry
Published: February 25, 2025
Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants: A Phase 3 Randomized Controlled Trial.
Journal: The Journal of clinical psychiatry
Published: June 25, 2024
Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone'.
Journal: Molecular psychiatry
Published: January 16, 2024
The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users.
Journal: Translational psychiatry
Published: March 14, 2023
Safety and Efficacy of Lofexidine for Medically Managed Opioid Withdrawal: A Randomized Controlled Clinical Trial.
Journal: Journal of addiction medicine
Published: December 12, 2018
A phase III, randomized, multi-center, double blind, placebo controlled study of safety and efficacy of lofexidine for relief of symptoms in individuals undergoing inpatient opioid withdrawal.
Journal: Drug and alcohol dependence
Published: September 09, 2016
Psychometric evaluation of the 10-item Short Opiate Withdrawal Scale-Gossop (SOWS-Gossop) in patients undergoing opioid detoxification.
Journal: Addictive behaviors
Published: September 22, 2015
Fine-grain analysis of the treatment effect of topiramate on methamphetamine addiction with latent variable analysis.
Journal: Drug and alcohol dependence
Published: January 11, 2012
Topiramate for the treatment of methamphetamine addiction: a multi-center placebo-controlled trial.
Journal: Addiction (Abingdon, England)
Published: January 07, 2012
Showing 1-11 of 11
Last Updated: 09/26/2026