Charlie Laffeber
Rotterdam, ZH, Netherlands
Last Updated: 09/26/2026
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Found 16 publications
Tetramerization of the DNA mismatch repair protein MutS enhances daughter strand incision preferentially in the vicinity of replication errors.
Journal: The Journal of biological chemistry
Published: June 26, 2025
APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells.
Journal: Stem cell reviews and reports
Published: April 27, 2023
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Journal: Nature structural & molecular biology
Published: February 07, 2023
Correction: Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
Journal: The Journal of experimental medicine
Published: December 08, 2022
Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
Journal: The Journal of experimental medicine
Published: March 21, 2022
The miniature CRISPR-Cas12m effector binds DNA to block transcription.
Journal: Molecular cell
Published: December 16, 2021
Experimental Evidence for Enhanced Receptor Binding by Rapidly Spreading SARS-CoV-2 Variants.
Journal: Journal of molecular biology
Published: April 06, 2021
The selection process of licensing a DNA mismatch for repair.
Journal: Nature structural & molecular biology
Published: June 20, 2020
Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA.
Journal: Science advances
Published: September 12, 2019
On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation.
Journal: Cancers
Published: December 18, 2018
The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair.
Journal: Nucleic acids research
Published: November 16, 2018
Last Updated: 09/26/2026