Chen Lu

Jiangsu Province Key Laboratory Of Anesthesiology
Xuzhou, 221004, China

Last Updated: 09/26/2026

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Found 18 publications

TIM3 alleviates microglia-mediated neuroinflammation in neuropathic pain by negatively regulating glycolysis-driven NLRP3 inflammasome activation.

TIM3 alleviates microglia-mediated neuroinflammation in neuropathic pain by negatively regulating glycolysis-driven NLRP3 inflammasome activation.

Journal: Acta biochimica et biophysica Sinica

Published: July 01, 2026

Targeting the oxidative stress-neuroinflammation axis: the mechanism of arctigenin's broad-spectrum analgesia with limited side effects.

Targeting the oxidative stress-neuroinflammation axis: the mechanism of arctigenin's broad-spectrum analgesia with limited side effects.

Journal: Frontiers in immunology

Published: November 26, 2025

TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.

TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.

Journal: Neuropharmacology

Published: May 01, 2025

Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.

Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.

Journal: Molecular pain

Published: April 24, 2024

Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.

Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.

Journal: The international journal of biochemistry & cell biology

Published: June 16, 2023

Exercise Regulates Myokines in Aging-Related Diseases through Muscle-Brain Crosstalk.

Exercise Regulates Myokines in Aging-Related Diseases through Muscle-Brain Crosstalk.

Journal: Gerontology

Published: June 06, 2023

Tumor necrosis factor-α-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-κB signaling pathways.

Tumor necrosis factor-α-induced protein 8-like 2 alleviates morphine antinociceptive tolerance through reduction of ROS-mediated apoptosis and MAPK/NF-κB signaling pathways.

Journal: Neuropharmacology

Published: December 11, 2022

Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter.

Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter.

Journal: Neuron

Published: May 09, 2022

Fluoxetine reverses hyperactivity of anterior cingulate cortex and attenuates chronic stress-induced hyperalgesia.

Fluoxetine reverses hyperactivity of anterior cingulate cortex and attenuates chronic stress-induced hyperalgesia.

Journal: Neuropharmacology

Published: January 31, 2022

Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway.

Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway.

Journal: Autophagy

Published: December 08, 2021

Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.

Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.

Journal: Cancer letters

Published: September 15, 2021

Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy.

Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy.

Journal: Basic research in cardiology

Published: September 14, 2021

Showing 1-12 of 18

Last Updated: 09/26/2026