Chen Zhou

State Key Laboratory Of Natural Medicines, Jiangsu Key Laboratory Of Carcinogenesis And Intervention, 24 Tongjiaxiang
Nanjing, 210009, China

Last Updated: 09/26/2026

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Found 14 publications

Oroxylin A attenuates sepsis-associated coagulopathy by targeting the ALOX12-lipid peroxidation.

Oroxylin A attenuates sepsis-associated coagulopathy by targeting the ALOX12-lipid peroxidation.

Journal: Biochemical pharmacology

Published: December 08, 2025

Targeting Cyclic GMP-AMP Synthase: Novel Therapeutic Inhibitors for Autoimmune Diseases.

Targeting Cyclic GMP-AMP Synthase: Novel Therapeutic Inhibitors for Autoimmune Diseases.

Journal: ChemMedChem

Published: November 21, 2025

The flavonoid GL-V9 induces oxidative stress mediated apoptosis in small cell lung cancer by promoting STEAP3 degradation.

The flavonoid GL-V9 induces oxidative stress mediated apoptosis in small cell lung cancer by promoting STEAP3 degradation.

Journal: Free radical biology & medicine

Published: November 20, 2025

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease.

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 29, 2025

Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis.

Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis.

Journal: Biochemical pharmacology

Published: May 18, 2025

GL-V9 inhibits Caspase-11 activation-induced pyroptosis by suppressing ALOX12-mediated lipid peroxidation to alleviate sepsis.

GL-V9 inhibits Caspase-11 activation-induced pyroptosis by suppressing ALOX12-mediated lipid peroxidation to alleviate sepsis.

Journal: British journal of pharmacology

Published: August 31, 2024

TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1.

TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1.

Journal: Redox biology

Published: May 29, 2024

Sorafenib-mediated cleavage of p62 initiates cellular senescence as a mechanism to evade its anti-hepatocellular carcinoma efficacy.

Sorafenib-mediated cleavage of p62 initiates cellular senescence as a mechanism to evade its anti-hepatocellular carcinoma efficacy.

Journal: Oncogene

Published: April 29, 2024

Cyclopeptide RA-V from Rubia yunnanensis restores activity of Adagrasib against colorectal cancer by reducing the expression of Nrf2.

Cyclopeptide RA-V from Rubia yunnanensis restores activity of Adagrasib against colorectal cancer by reducing the expression of Nrf2.

Journal: Pharmacological research

Published: April 01, 2024

Eubacterium coprostanoligenes alleviates chemotherapy-induced intestinal mucositis by enhancing intestinal mucus barrier.

Eubacterium coprostanoligenes alleviates chemotherapy-induced intestinal mucositis by enhancing intestinal mucus barrier.

Journal: Acta pharmaceutica Sinica. B

Published: October 03, 2023

The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.

The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells.

Journal: British journal of pharmacology

Published: May 03, 2022

Discovery of deoxylimonin δ-lactam derivative with favorable anti-inflammation and antinociception efficacy from chemical modified limonin/deoxylimonin analogs.

Discovery of deoxylimonin δ-lactam derivative with favorable anti-inflammation and antinociception efficacy from chemical modified limonin/deoxylimonin analogs.

Journal: Bioorganic chemistry

Published: April 01, 2020

Showing 1-12 of 14

Last Updated: 09/26/2026