Chengjuan Chen

State Key Laboratory Of Bioactive Substance And Function Of Natural Medicines, Chinese Academy Of Medical Sciences & Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 19 publications

Immunomodulatory supramolecular hydrogel for rheumatoid arthritis management via adenosine A2A receptor-mediated macrophage remodeling.

Immunomodulatory supramolecular hydrogel for rheumatoid arthritis management via adenosine A2A receptor-mediated macrophage remodeling.

Journal: Bioactive materials

Published: August 20, 2025

Benzyl sulfide, sulfoxide and sulfinate metabolites from Gastrodia elata and their synthesis, derivatization and anti-inflammatory activity.

Benzyl sulfide, sulfoxide and sulfinate metabolites from Gastrodia elata and their synthesis, derivatization and anti-inflammatory activity.

Journal: Chinese journal of natural medicines

Published: January 09, 2025

Butyrolactone I blocks the transition of acute kidney injury to chronic kidney disease in mice by targeting JAK1.

Butyrolactone I blocks the transition of acute kidney injury to chronic kidney disease in mice by targeting JAK1.

Journal: MedComm

Published: June 28, 2024

A synthetic derivative of bioactive constituents from Isatis indigotica ameliorates hypersensitivity and arthritis by inhibiting JAK2-STAT3 pathway in mice.

A synthetic derivative of bioactive constituents from Isatis indigotica ameliorates hypersensitivity and arthritis by inhibiting JAK2-STAT3 pathway in mice.

Journal: International immunopharmacology

Published: June 02, 2023

JAK inhibition ameliorated experimental autoimmune encephalomyelitis by blocking GM-CSF-driven inflammatory signature of monocytes.

JAK inhibition ameliorated experimental autoimmune encephalomyelitis by blocking GM-CSF-driven inflammatory signature of monocytes.

Journal: Acta pharmaceutica Sinica. B

Published: March 15, 2023

Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells.

Bone-derived MSCs encapsulated in alginate hydrogel prevent collagen-induced arthritis in mice through the activation of adenosine A2A/2B receptors in tolerogenic dendritic cells.

Journal: Acta pharmaceutica Sinica. B

Published: February 02, 2023

Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast-Myofibroblast Transformation against Pulmonary Fibrosis.

Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast-Myofibroblast Transformation against Pulmonary Fibrosis.

Journal: ACS chemical biology

Published: September 08, 2022

A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine-related JAK-STAT signal.

A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine-related JAK-STAT signal.

Journal: Science advances

Published: August 19, 2022

JAK3 inhibitors for the treatment of inflammatory and autoimmune diseases: a patent review (2016-present).

JAK3 inhibitors for the treatment of inflammatory and autoimmune diseases: a patent review (2016-present).

Journal: Expert opinion on therapeutic patents

Published: December 24, 2021

Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis.

Therapeutic potential of the target on NLRP3 inflammasome in multiple sclerosis.

Journal: Pharmacology & therapeutics

Published: December 31, 2020

Exploring a novel triptolide derivative possess anti-colitis effect via regulating T cell differentiation.

Exploring a novel triptolide derivative possess anti-colitis effect via regulating T cell differentiation.

Journal: International immunopharmacology

Published: June 26, 2020

Methotrexate enhances antigen presentation and maturation of tumour antigen-loaded dendritic cells through NLRP3 inflammasome activation: a strategy for dendritic cell-based cancer vaccine.

Methotrexate enhances antigen presentation and maturation of tumour antigen-loaded dendritic cells through NLRP3 inflammasome activation: a strategy for dendritic cell-based cancer vaccine.

Journal: Therapeutic advances in medical oncology

Published: February 13, 2020

Showing 1-12 of 19

Last Updated: 09/26/2026