Chengkui K. Yang

State Key Laboratory Of Common Mechanism Research For Major Diseases, And Key Laboratory Of Synthetic Biology Regulatory Elements, Chinese Academy Of Medical Sciences & Peking Union Medical College
Suzhou, 215123, China

Last Updated: 09/26/2026

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Found 13 publications

Discovery of Zharp1-163 as a dual inhibitor of ferroptosis and necroptosis for the treatment of inflammatory disorders and kidney injury.

Discovery of Zharp1-163 as a dual inhibitor of ferroptosis and necroptosis for the treatment of inflammatory disorders and kidney injury.

Journal: Cell death discovery

Published: March 31, 2025

Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease.

Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel disease.

Journal: Biochemical pharmacology

Published: April 13, 2023

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16.

Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16.

Journal: The Journal of cell biology

Published: March 28, 2023

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.

Journal: Blood

Published: June 09, 2022

Interferon-mediated repression of miR-324-5p potentiates necroptosis to facilitate antiviral defense.

Interferon-mediated repression of miR-324-5p potentiates necroptosis to facilitate antiviral defense.

Journal: EMBO reports

Published: December 07, 2021

Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosis.

Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosis.

Journal: Apoptosis : an international journal on programmed cell death

Published: May 18, 2020

A novel missense mutation, p.Phe360Cys, in FIX gene results in haemophilia B in a female patient with skewed X-inactivation.

A novel missense mutation, p.Phe360Cys, in FIX gene results in haemophilia B in a female patient with skewed X-inactivation.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: December 20, 2017

Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis.

Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis.

Journal: Cell death & disease

Published: March 28, 2017

Correction: Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

Correction: Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

Journal: The Journal of cell biology

Published: March 16, 2016

Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors.

Heat shock protein 90 regulates necroptosis by modulating multiple signaling effectors.

Journal: Cell death & disease

Published: March 04, 2016

Aqueous synthesized quantum dots interfere with the NF-κB pathway and confer anti-tumor, anti-viral and anti-inflammatory effects.

Aqueous synthesized quantum dots interfere with the NF-κB pathway and confer anti-tumor, anti-viral and anti-inflammatory effects.

Journal: Biomaterials

Published: February 02, 2016

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.

Journal: The Journal of cell biology

Published: January 20, 2016

Showing 1-12 of 13

Last Updated: 09/26/2026