Chenicheri K. Keerthana

Thiruvananthapuram, KL, India

Last Updated: 09/26/2026

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Found 16 publications

Uttroside B, a US FDA-designated 'Orphan Drug', mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3.

Uttroside B, a US FDA-designated 'Orphan Drug', mitigates the development of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3.

Journal: Cell death discovery

Published: August 05, 2025

Orphan drug uttroside B impedes MASH progression and HCC development in experimental models.

Orphan drug uttroside B impedes MASH progression and HCC development in experimental models.

Journal: JHEP reports : innovation in hepatology

Published: December 19, 2024

Influence of surface texture: A comparative study on antibacterial activities of morphologically tailored zinc oxide.

Influence of surface texture: A comparative study on antibacterial activities of morphologically tailored zinc oxide.

Journal: Biochemical and biophysical research communications

Published: August 15, 2024

A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.

A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.

Journal: Anti-cancer agents in medicinal chemistry

Published: March 12, 2024

Enhanced extracellular vesicles mediated uttroside B (Utt-B) delivery to Hepatocellular carcinoma cell: Pharmacokinetics based on PBPK modelling.

Enhanced extracellular vesicles mediated uttroside B (Utt-B) delivery to Hepatocellular carcinoma cell: Pharmacokinetics based on PBPK modelling.

Journal: Biochemical and biophysical research communications

Published: January 23, 2024

Phytochemicals as Potential Lead Molecules against Hepatocellular Carcinoma.

Phytochemicals as Potential Lead Molecules against Hepatocellular Carcinoma.

Journal: Current medicinal chemistry

Published: August 03, 2023

Targeting receptor tyrosine kinase signaling: Avenues in the management of cutaneous squamous cell carcinoma.

Targeting receptor tyrosine kinase signaling: Avenues in the management of cutaneous squamous cell carcinoma.

Journal: iScience

Published: May 26, 2023

The role of AMPK in cancer metabolism and its impact on the immunomodulation of the tumor microenvironment.

The role of AMPK in cancer metabolism and its impact on the immunomodulation of the tumor microenvironment.

Journal: Frontiers in immunology

Published: December 02, 2022

Corrigendum: Blockade of uttroside B-induced autophagic pro-survival signals augments its chemotherapeutic efficacy against hepatocellular carcinoma.

Corrigendum: Blockade of uttroside B-induced autophagic pro-survival signals augments its chemotherapeutic efficacy against hepatocellular carcinoma.

Journal: Frontiers in oncology

Published: July 11, 2022

Corrigendum: Cucurbitacin B, purified and characterized from the rhizome of Corallocarpus epigaeus exhibits anti-melanoma potential.

Corrigendum: Cucurbitacin B, purified and characterized from the rhizome of Corallocarpus epigaeus exhibits anti-melanoma potential.

Journal: Frontiers in oncology

Published: July 08, 2022

Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.

Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 27, 2022

Cucurbitacin B, Purified and Characterized From the Rhizome of Corallocarpus epigaeus Exhibits Anti-Melanoma Potential.

Cucurbitacin B, Purified and Characterized From the Rhizome of Corallocarpus epigaeus Exhibits Anti-Melanoma Potential.

Journal: Frontiers in oncology

Published: March 24, 2022

Showing 1-12 of 16

Last Updated: 09/26/2026