Chiara Zuccato

Milan, 20133, Italy

Last Updated: 09/26/2026

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Found 31 publications

Cholesterol restores cortico-striatal synaptic connectivity in Huntington's disease through BDNF-TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies.

Cholesterol restores cortico-striatal synaptic connectivity in Huntington's disease through BDNF-TrkB signalling, supporting a role for cholesterol pathways implicated by human genetic modifier studies.

Journal: Pharmacological research

Published: May 23, 2026

Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7.

Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7.

Journal: Nature communications

Published: August 14, 2025

Huntingtin and its allies at the cortico-striatal synapse.

Huntingtin and its allies at the cortico-striatal synapse.

Journal: Cell death & disease

Published: July 31, 2025

Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington's disease.

Cholesterol nose-to-brain delivery as a possible therapeutic strategy in Huntington's disease.

Journal: Translational neurodegeneration

Published: June 13, 2025

Author Correction: Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Author Correction: Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Journal: Nature communications

Published: May 21, 2025

A human CAGinSTEM platform for decoding HTT repeats' somatic instability links CAG interruption to HD pathology in neurons.

A human CAGinSTEM platform for decoding HTT repeats' somatic instability links CAG interruption to HD pathology in neurons.

Journal: Cell reports

Published: May 13, 2025

Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids.

Journal: Nature communications

Published: May 10, 2024

Neuroprotection by ADAM10 inhibition requires TrkB signaling in the Huntington's disease hippocampus.

Neuroprotection by ADAM10 inhibition requires TrkB signaling in the Huntington's disease hippocampus.

Journal: Cellular and molecular life sciences : CMLS

Published: January 30, 2024

Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models.

Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid Models.

Journal: International journal of molecular sciences

Published: October 05, 2022

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.

Journal: Cell death and differentiation

Published: June 24, 2021

Geographic differences in the incidence of Huntington's disease in Sardinia, Italy.

Geographic differences in the incidence of Huntington's disease in Sardinia, Italy.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Published: December 26, 2020

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.

ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.

Journal: Human molecular genetics

Published: October 11, 2020

Showing 1-12 of 31

Last Updated: 09/26/2026